PREPRINTS

LeBlanc CJ, Stefani J, Soriano M, Lam A, Zintel MA, Kotha SR, Chase E, Pimentel-Solorio G, Vunnum A, Flug KL, Fultineer AT, Hummel N, Staller MV. 2024. Conservation of function without conservation of amino acid sequence in intrinsically disordered transcriptional activation domains. bioRxiv. doi:10.1101/2024.12.03.626510

Flores E, Camacho A, Cuevas-Zepeda E, McCoy MB, Yu F, Staller MV, Sukenik S. 2024. Correlating disordered activation domain ensembles with gene expression levels. bioRxiv. doi:10.1101/2024.10.19.619222

PUBLICATIONS

N Morffy, L Van den Broeck, C Miller, RJ Emenecker, JA Bryant Jr., TM Lee, K Sageman-Furnas, SR Kotha, A Lam, S Mahatma, V Pande, A Waoo, RC Wright, AS Holehouse, MV Staller, R Sozzani, LC Strader. 2024. Plant Activation Domain Identification. Nature 632, 166–173 (2024). https://doi.org/10.1038/s41586-024-07707-3

N Hummel, K Markel, J Stefani, MV Staller*, P Shih*. 2024. Systematic identification of transcriptional activation domains from non-transcription factor proteins in plants and yeast. Cell Systems. 14:501–511.e4. https://doi.org/10.1016/j.cels.2024.05.007 *corresponding authors

A Udupa, SR Kotha, MV Staller. 2023. Commonly asked questions about transcriptional activation domains. Curr Opin Struct Biol 84:102732.

SR Kotha and MV Staller. 2023 The balance of acidic and hydrophobic residues predicts acidic transcriptional activation domains from protein sequence. Genetics, iyad131, https://doi.org/10.1093/genetics/iyad131

S Mahatma, L Van den Broeck, N Morffy, MV Staller, LC Strader, R Sozzani. 2023. Prediction and functional characterization of transcriptional activation domains2023 57th Annual Conference on Information Sciences and Systems (CISS). pp. 1–6.

MV Staller. Transcription factors perform a 2-step search of the nucleus. Genetics https://doi.org/10.1093/genetics/iyac111.

MV Staller*, E Ramirez, SR Kotha, AS Holehouse, RV Pappu, BA Cohen*. Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains. 2022. Cell Systems. 13, 334-345.e5 *co-corresponding authors

K Loell, Y Wu, MV Staller, BA Cohen. Activation domains can decouple the mean and noise of gene expression. 2022 Cell Reports, Volume 40, Issue 3, 111118

MV Staller, AS Holehouse, D Swain-Lenz, R Das, RV Pappu, BA Cohen. A High-Throughput Mutational Scan of an Intrinsically Disordered Acidic Transcriptional Activation Domain. Cell Systems. 2018 6(4):444-455.

NC Rockwell, W Yang, NM Warrington, MV Staller, M Griffith, OL Griffith, CA Gurnett, BA Cohen, D Baldridge, JB Rubin. Sex and mutation-specific p53 gain-of-function activity in gliomagenesis. Cancer Research Communications. 2021 1 (3): 148–163.

BJ Vincent, MV Staller, F Lopez-Rivera, MDJ Bragdon, ECG Pym, KM Biette, Z Wunderlich, TT Harden, J Estrada, AH DePace. Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos. PLoS Genetics. 2018 Sep 7;14(9):e1007644.

D Swain-Lenz, I Nikolskiy, J Cheng, P Sudarsanam, D Nayler, MV Staller, BA Cohen. Causal Genetic Variation Underlying Metabolome Differences. Genetics. 2017 206(4):2199-2206.

HG Chaudhari and MV Staller, Preview: Scaling-Up Signaling Pathway Analysis. Cell Systems. 2016 2(5): 295-296.

BJ Vincent, C Scholes, MV Staller, Z Wunderlich, J Estrada, J Park, MD Bragdon, K Biette, AH DePace. Yearly Planning Meetings: Individualized Development Plans Aren’t Just More Paperwork. Molecular Cell. 2015 58(5): 718-721.
-All authors contributed equally to this work.

MV Staller, BJ Vincent, MD Bragdon, J Estrada, Z Wunderlich, AH DePace. Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo. Proceedings of the National Academy of Sciences. 2015 112(3): 785-790.

MV Staller, CC Fowlkes, MD Bragdon, J Estrada, Z Wunderlich, AH DePace. A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate. Development. 2015 142: 587-596.

Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D, Bauerle C, Bisaria N, Bradley PH, Breunig JS, Bush E, Cappel D, Capra E, Chen W, Clore J, Combs PA, Doucette C, Demuren O, Fellowes P, Freeman S, Frenkel E, Gadala-Maria D, Gawande R, Glass D, Grossberg S, Gupta A, Hammonds-Odie L, Hoisos A, Hsi J, Hsu YH, Inukai S, Karczewski KJ, Ke X, Kojima M, Leachman S, Lieber D, Liebowitz A, Liu J, Liu Y, Martin T, Mena J, Mendoza R, Myhrvold C, Millian C, Pfau S, Raj S, Rich M, Rokicki J, Rounds W, Salazar M, Salesi M, Sharma R, Silverman S, Singer C, Sinha S, Staller MV, Stern P, Tang H, Weeks S, Weidmann M, Wolf A, Young C, Yuan J, Crutchfield C, McClean M, Murphy CT, Llinás M, Botstein D, Troyanskaya OG, Dunham MJ. A new system for comparative functional genomics of Saccharomyces yeasts. Genetics. September 2013 195(1): 275-287.

MV Staller, D Yan, S Randklev, MD Bragdon, Z Wunderlich, R Tao, LA Perkins, AH DePace, N Perrimon. Depleting Gene Activities in Early Drosophila Embryos with the “maternal-Gal4-shRNA” System. Genetics. January 2013 193(1): 51-61.

Further afield

MV Staller. Forum on Princeton's Boris Godunov: Testimonials from the Company: The Actors on Their Biggest Anxieties, Best Moments, and Steepest Learning Curves: Getting Muscles under Control. Pushkin Review. (2007) Vol. 10: 20-22.